آلفا-اتیل‌تریپتامین

آلفا-اتیل‌تریپتامین
نام‌گذاری آیوپاک
	1-(1H-indol-3-yl)butan-2-amine
اطلاعات درمانی
وضعیت قانونی	CA: رده سه ; UK: کلاس آ ; US: رده یک ;
شناسه‌ها
سی‌ای‌اس	2235-90-7 118-68-3
ای‌تی‌سی	None
پاب‌کم	CID: 8367
دراگ‌بنک	DB01546
کم‌اسپایدر	8064
UNII	GR181O3R32
مترادفs	۳-(۲-آمینوبوتیل)ایندول
اطلاعات شیمیایی
فرمول شیمیایی	C12H16N2
وزن مولکولی	۱۸۸٫۲۷ g·mol−1
	شناسه شیمیایی بین‌المللی InChI=1S/C12H16N2/c1-2-10(13)7-9-8-14-12-6-4-3-5-11(9)12/h3-6,8,10,14H,2,7,13H2,1H3 ; Key:ZXUMUPVQYAFTLF-UHFFFAOYSA-N ;
اطلاعات فیزیکی
دمای ذوب	۲۲۲ تا ۲۲۳ درجه سلسیوس (۴۳۲ تا ۴۳۳ درجه فارنهایت)
(بررسی)

آلفا-اتیل‌تریپتامین (αET ,AET)، همچنین به عنوان اتریپتامین (INN ,BAN ,USAN) نیز شناخته می‌شود، یک داروی روان‌گردان، محرک و entactogenic از دسته تریپتامین‌ها است.[1][2] این ماده در اصل به عنوان داروی ضد افسردگی با نام تجاری Monase توسط Upjohn در دهه ۱۹۶۰ تولید و به بازار عرضه شد.[3]

منابع

""Erowid AET (alpha-ethyltryptamine) Vault"".
Alexander Shulgin; Ann Shulgin. "#11, a-ET: Alpha-Ethyltryptamine; Indole,3-(2-Aminobutyl); Tryptamine,Alpha-Ethyl; 3-(2-Aminobutyl)Indole; Monase,". "Tryptamines i Have Known And Loved: The Continuation", Part 2, "The Chemistry Continues". Erowid Online Library. p. 11. Retrieved 15 November 2013.
, "Method of Treating Mental Depression"
Alexander Shulgin; Ann Shulgin (1997). ""Part 2, The Chemistry Continues: #11, a-ET: Alpha-Ethyltryptamine; Indole,3-(2-Aminobutyl); Tryptamine,Alpha-Ethyl; 3-(2-Aminobutyl)Indole; Monase," part v, "EXTENSIONS AND COMMENTARY."" (Book). Tryptamines i Have Known and Loved: The Continuation, (1st. ed.). Berkeley, CA: Transform Press, ©1997. ISBN 978-0-9630096-9-2. Retrieved 15 November 2013. This base, a-ET or etryptamine, was a promising anti-depressant, explored clinically as the acetate salt by Upjohn under the name of Monase. Its central stimulant activity is probably not due to its monoamineoxidase inhibition activity, but appears to stem from its structural relationship to the indolic psychedelics. It was withdrawn from potential commercial use with the appearance of an unacceptable incidence of a medical condition known as agranulocytosis, but the extra mural research into its action, among the lay population, goes on,
Huang XM, Johnson MP, Nichols DE (July 1991). "Reduction in brain serotonin markers by alpha-ethyltryptamine (Monase)". European Journal of Pharmacology. 200 (1): 187–190. doi:10.1016/0014-2999(91)90686-K. PMID 1722753.

پیوند به بیرون

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[1] ""Erowid AET (alpha-ethyltryptamine) Vault"".

[2] Alexander Shulgin; Ann Shulgin. "#11, a-ET: Alpha-Ethyltryptamine; Indole,3-(2-Aminobutyl); Tryptamine,Alpha-Ethyl; 3-(2-Aminobutyl)Indole; Monase,". "Tryptamines i Have Known And Loved: The Continuation", Part 2, "The Chemistry Continues". Erowid Online Library. p. 11. Retrieved 15 November 2013.

[3] , "Method of Treating Mental Depression"

[tihkalbook-4] Alexander Shulgin; Ann Shulgin (1997). ""Part 2, The Chemistry Continues: #11, a-ET: Alpha-Ethyltryptamine; Indole,3-(2-Aminobutyl); Tryptamine,Alpha-Ethyl; 3-(2-Aminobutyl)Indole; Monase," part v, "EXTENSIONS AND COMMENTARY."" (Book). Tryptamines i Have Known and Loved: The Continuation, (1st. ed.). Berkeley, CA: Transform Press, ©1997. ISBN 978-0-9630096-9-2. Retrieved 15 November 2013. This base, a-ET or etryptamine, was a promising anti-depressant, explored clinically as the acetate salt by Upjohn under the name of Monase. Its central stimulant activity is probably not due to its monoamineoxidase inhibition activity, but appears to stem from its structural relationship to the indolic psychedelics. It was withdrawn from potential commercial use with the appearance of an unacceptable incidence of a medical condition known as agranulocytosis, but the extra mural research into its action, among the lay population, goes on,

[pmid1722753-5] Huang XM, Johnson MP, Nichols DE (July 1991). "Reduction in brain serotonin markers by alpha-ethyltryptamine (Monase)". European Journal of Pharmacology. 200 (1): 187–190. doi:10.1016/0014-2999(91)90686-K. PMID 1722753.