غیراستروئیدی

یک ترکیب غیر استروئیدی دارویی است که نه استروئید است و نه مشتقی از آن.[1][2] داروهای ضدالتهاب غیراستروئیدی (NSAID) از کورتیکواستروئیدها به عنوان دسته ای از عوامل ضد التهاب متمایز می‌شوند.[3]

فهرست تعدیل کننده‌های گیرنده استروئید غیراستروئیدی

شامل موارد زیر است:[4][5]

استروژن‌ها: benzestrol, bifluranol, estrobin (DBE), diethylstilbestrol (stilbestrol), دینسترول، erteberel, فس فسترول، hexestrol (dihydroxystilbestrol), مالزیتوز، methestrol, methestrol dipropionate, paroxypropione, prinaberel, و تری‌فنیل‌اتیلن، همچون بسیاری از xenoestrogen‌ها
SERMs: acolbifene, آفیموکسیفن، آرزوکسیفن، bazedoxifene, broparestrol, کلروتریانیسن، کلومیفن سیترات، clomifenoxide, cyclofenil, droloxifene, enclomifene, endoxifen, اتاموکسی‌تری‌فتول، fispemifene, idoxifene, lasofoxifene, levormeloxifene, miproxifene, nafoxidine, nitromifene, ormeloxifene, ospemifene, panomifene, pipendoxifene, رالوکسیفن، تاموکسیفن، toremifene, trioxifene, zindoxifene, zuclomifene
آنتی‌آندروژن‌ها: apalutamide, بیکالوتامید، سایمتیدین، darolutamide, DIMP, ام‌دی‌وی۳۱۰۰, EPI-001, EPI-506 , فلوتامید، hydroxyflutamide, inocoterone, inocoterone acetate, nilutamide, RU-58642, RU-58841, و topilutamide
SARMs: AC-262,356, acetothiolutamide, andarine, BMS-564,929, enobosarm (ostarine), LGD-2226, LGD-3303, LGD-4033 , S-23, and S-40503
Aromatase inhibitor‌ها: آناستروزول، آمینوگلوتتیمید، فادروزول، finrozole, لتروزول، liarozole, norendoxifen, rogletimide (pyridoglutethimide), vorozole
Other steroidogenesis inhibitors: آمینوگلوتتیمید، کتوکونازول، ارترونل، seviteronel, others
Miscellaneous: tanaproget (پروژستوژن), finerenone (antimineralocorticoid), esaxerenone (antimineralocorticoid), apararenone (antimineralocorticoid), AZD5423 (گلوکوکورتیکوئید), mapracorat (SGRM)

منابع

Edward J. Pavlik (6 December 2012). Estrogens, Progestins, and Their Antagonists: Health Issues. Springer Science & Business Media. pp. 166–. ISBN 978-1-4612-4096-9.
Thomas Nogrady Professor of Medicinal Chemistry Concordia University (Emeritus); Donald F. Weaver Canada Research Chair and Professor of Medicine and Chemistry Dalhousie University (27 July 2005). Medicinal Chemistry : A Molecular and Biochemical Approach: A Molecular and Biochemical Approach. Oxford University Press, USA. pp. 322–. ISBN 978-0-19-802645-7.
Buer JK (Oct 2014). "Origins and impact of the term 'NSAID'". Inflammopharmacology. 22 (5): 263–7. doi:10.1007/s10787-014-0211-2. PMID 25064056. |hdl-access= requires |hdl= (help)
Edward J. Pavlik (6 December 2012). Estrogens, Progestins, and Their Antagonists: Health Issues. Springer Science & Business Media. pp. 166–. ISBN 978-1-4612-4096-9.
Thomas Nogrady Professor of Medicinal Chemistry Concordia University (Emeritus); Donald F. Weaver Canada Research Chair and Professor of Medicine and Chemistry Dalhousie University (27 July 2005). Medicinal Chemistry: A Molecular and Biochemical Approach: A Molecular and Biochemical Approach. Oxford University Press, USA. pp. 322–. ISBN 978-0-19-802645-7.

مطالعه بیشتر

Miquel JF, Gilbert J (1988). "A chemical classification of nonsteroidal antagonists of sex-steroid hormone action". J. Steroid Biochem. 31 (4B): 525–44. PMID 3059055.
Buijsman, Rogier; Hermkens, Pedro; Rijn, Rachel; Stock, H.; Teerhuis, N. (2005). "Non-Steroidal Steroid Receptor Modulators". Current Medicinal Chemistry. 12 (9): 1017–1075. doi:10.2174/0929867053764671. ISSN 0929-8673. PMID 16821162.
Hermkens PH, Kamp S, Lusher S, Veeneman GH (2006). "Non-steroidal steroid receptor modulators". IDrugs. 9 (7): 488–94. doi:10.2174/0929867053764671. PMID 16821162.

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[Pavlik20122-1] Edward J. Pavlik (6 December 2012). Estrogens, Progestins, and Their Antagonists: Health Issues. Springer Science & Business Media. pp. 166–. ISBN 978-1-4612-4096-9.

[(Emeritus)University20052-2] Thomas Nogrady Professor of Medicinal Chemistry Concordia University (Emeritus); Donald F. Weaver Canada Research Chair and Professor of Medicine and Chemistry Dalhousie University (27 July 2005). Medicinal Chemistry : A Molecular and Biochemical Approach: A Molecular and Biochemical Approach. Oxford University Press, USA. pp. 322–. ISBN 978-0-19-802645-7.

[Buer_2014-3] Buer JK (Oct 2014). "Origins and impact of the term 'NSAID'". Inflammopharmacology. 22 (5): 263–7. doi:10.1007/s10787-014-0211-2. PMID 25064056. |hdl-access= requires |hdl= (help)

[Pavlik20123-4] Edward J. Pavlik (6 December 2012). Estrogens, Progestins, and Their Antagonists: Health Issues. Springer Science & Business Media. pp. 166–. ISBN 978-1-4612-4096-9.

[(Emeritus)University20053-5] Thomas Nogrady Professor of Medicinal Chemistry Concordia University (Emeritus); Donald F. Weaver Canada Research Chair and Professor of Medicine and Chemistry Dalhousie University (27 July 2005). Medicinal Chemistry: A Molecular and Biochemical Approach: A Molecular and Biochemical Approach. Oxford University Press, USA. pp. 322–. ISBN 978-0-19-802645-7.