CLEC1A

CLEC1A
معین‌کننده‌ها
نام‌های دیگر	CLEC1A, CLEC-1, CLEC1, C-type lectin domain family 1 member A
شناسه‌های بیرونی	OMIM: 606782 MGI: 2444151 HomoloGene: 9549 GeneCards: CLEC1A
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)[1]
End	129,452,000 bp[1]
الگوی گسترش RNA
	More reference expression data
هستی‌شناسی ژن
عملکرد ملکولی	• transmembrane signaling receptor activity; • carbohydrate binding;
ترکیبات سلولی	• integral component of membrane; • integral component of plasma membrane; • intracellular anatomical structure; • membrane;
فرایند زیستی	• cell surface receptor signaling pathway; • defense response;
	Sources:آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
	51267
	243653
	ENSG00000150048
	ENSMUSG00000033082
	Q8NC01
	Q8BWY2
	NM_001297748، NM_001297749، NM_001297750، NM_001297751، NM_016511 XM_011520687، NM_001297748، NM_001297749، NM_001297750، NM_001297751، NM_016511
	NM_001347475 NM_175526، NM_001347475
	NP_001284678، NP_001284679، NP_001284680، NP_057595، XP_011518989 NP_001284677، NP_001284678، NP_001284679، NP_001284680، NP_057595، XP_011518989; NP_001284677.1
	NP_780735 NP_001334404، NP_780735
	ویکی‌داده
مشاهده/ویرایش Human	View/Edit Mouse

عضو A از خانوادهٔ ۱ دومِـین لکتین نوع سی (انگلیسی: C-type lectin domain family 1 member A‎) یک پروتئین است که در انسان توسط ژن «CLEC1A» کُدگذاری می‌شود.[4][5][6]

این پروتئین نقش مهمی در تنظیم عملکرد سلول‌های دندریتیک دارد.

منابع

GRCm38: Ensembl release 89: ENSMUSG00000033082 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Colonna M, Samaridis J, Angman L (Mar 2000). "Molecular characterization of two novel C-type lectin-like receptors, one of which is selectively expressed in human dendritic cells". Eur J Immunol. 30 (2): 697–704. doi:10.1002/1521-4141(200002)30:2<697::AID-IMMU697>3.0.CO;2-M. PMID 10671229.
Sobanov Y, Bernreiter A, Derdak S, Mechtcheriakova D, Schweighofer B, Duchler M, Kalthoff F, Hofer E (Dec 2001). "A novel cluster of lectin-like receptor genes expressed in monocytic, dendritic and endothelial cells maps close to the NK receptor genes in the human NK gene complex". Eur J Immunol. 31 (12): 3493–503. doi:10.1002/1521-4141(200112)31:12<3493::AID-IMMU3493>3.0.CO;2-9. PMID 11745369.
"Entrez Gene: CLEC1A C-type lectin domain family 1, member A".

مشارکت‌کنندگان ویکی‌پدیا. «CLEC1A». در دانشنامهٔ ویکی‌پدیای انگلیسی، بازبینی‌شده در ۲۳ دسامبر ۲۰۱۹.

پیوند به بیرون

مکان ژنوم CLEC1A انسانی و صفحهٔ جزئیات ژنی CLEC1A در سامانه جستجوی بانک ژنی دانشگاه کالیفرنیا، سانتا کروز.

برای مطالعهٔ بیشتر

Drickamer K (1999). "C-type lectin-like domains". Curr. Opin. Struct. Biol. 9 (5): 585–90. doi:10.1016/S0959-440X(99)00009-3. PMID 10508765.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ebner S, Sharon N, Ben-Tal N (2003). "Evolutionary analysis reveals collective properties and specificity in the C-type lectin and lectin-like domain superfamily". Proteins. 53 (1): 44–55. doi:10.1002/prot.10440. PMID 12945048.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000033082 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10671229-4] Colonna M, Samaridis J, Angman L (Mar 2000). "Molecular characterization of two novel C-type lectin-like receptors, one of which is selectively expressed in human dendritic cells". Eur J Immunol. 30 (2): 697–704. doi:10.1002/1521-4141(200002)30:2<697::AID-IMMU697>3.0.CO;2-M. PMID 10671229.

[pmid11745369-5] Sobanov Y, Bernreiter A, Derdak S, Mechtcheriakova D, Schweighofer B, Duchler M, Kalthoff F, Hofer E (Dec 2001). "A novel cluster of lectin-like receptor genes expressed in monocytic, dendritic and endothelial cells maps close to the NK receptor genes in the human NK gene complex". Eur J Immunol. 31 (12): 3493–503. doi:10.1002/1521-4141(200112)31:12<3493::AID-IMMU3493>3.0.CO;2-9. PMID 11745369.

[entrez-6] "Entrez Gene: CLEC1A C-type lectin domain family 1, member A".