فاکتور رشد فیبروبلاست ۴

FGF4
ساختارهای موجود
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1IJT
معین‌کننده‌ها
نام‌های دیگر	FGF4, HBGF-4, HST, HST-1, HSTF1, K-FGF, KFGF, fibroblast growth factor 4, HSTF-1, FGF-4
شناسه‌های بیرونی	OMIM: 164980 MGI: 95518 HomoloGene: 1522 GeneCards: FGF4
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)[1]
End	144,865,243 bp[1]
الگوی گسترش RNA
	More reference expression data
هستی‌شناسی ژن
عملکرد ملکولی	• heparin binding; • fibroblast growth factor receptor binding; • growth factor activity; • protein tyrosine kinase activity; • phosphatidylinositol-4,5-bisphosphate 3-kinase activity; • 1-phosphatidylinositol-3-kinase activity;
ترکیبات سلولی	• extracellular region; • intracellular anatomical structure;
فرایند زیستی	• cartilage condensation; • MAPK cascade; • negative regulation of apoptotic process; • positive regulation of ERK1 and ERK2 cascade; • apoptotic process involved in morphogenesis; • ورارسانی پیام; • cell-cell signaling; • regulation of endothelial cell chemotaxis to fibroblast growth factor; • multicellular organism development; • embryonic limb morphogenesis; • mesenchymal cell proliferation; • positive regulation of cell division; • ساماندهی بیان ژن; • positive regulation of gene expression; • stem cell population maintenance; • chondroblast differentiation; • cranial suture morphogenesis; • positive regulation of transcription by RNA polymerase II; • دگرگونی یاخته‌; • positive regulation of protein phosphorylation; • odontogenesis of dentin-containing tooth; • embryonic hindlimb morphogenesis; • fibroblast growth factor receptor signaling pathway; • peptidyl-tyrosine phosphorylation; • positive regulation of cell population proliferation; • phosphatidylinositol phosphate biosynthetic process; • phosphatidylinositol-3-phosphate biosynthetic process; • cellular response to leukemia inhibitory factor; • regulation of signaling receptor activity; • positive regulation of protein kinase B signaling;
	Sources:آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
	2249
	14175
	ENSG00000075388
	ENSMUSG00000050917
	P08620
	P11403
	NM_002007
	NM_010202
	NP_001998
	NP_034332
	ویکی‌داده
مشاهده/ویرایش Human	View/Edit Mouse

فاکتور رشد فیبروبلاست ۴ (انگلیسی: FGF4‎) یک پروتئین در انسان است که بوسیلهٔ ژن FGF4 رمزگذاری می‌شود.[4][5] این پروتئین از خانوادهٔ عامل رشد فیبروبلاست (FGF) می‌باشد.

منابع

GRCm38: Ensembl release 89: ENSMUSG00000050917 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Galland F, Stefanova M, Lafage M, Birnbaum D (Jul 1992). "Localization of the 5' end of the MCF2 oncogene to human chromosome 15q15----q23". Cytogenetics and Cell Genetics. 60 (2): 114–6. doi:10.1159/000133316. PMID 1611909.
"Entrez Gene: FGF4 fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene)".

مشارکت‌کنندگان ویکی‌پدیا. «FGF4». در دانشنامهٔ ویکی‌پدیای انگلیسی، بازبینی‌شده در ۲۵ مه ۲۰۱۷.

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[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000050917 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid_1611909-4] Galland F, Stefanova M, Lafage M, Birnbaum D (Jul 1992). "Localization of the 5' end of the MCF2 oncogene to human chromosome 15q15----q23". Cytogenetics and Cell Genetics. 60 (2): 114–6. doi:10.1159/000133316. PMID 1611909.

[entrez-5] "Entrez Gene: FGF4 fibroblast growth factor 4 (heparin secretory transforming protein 1, Kaposi sarcoma oncogene)".