انتقال‌دهنده ۳ اسید آمینه خنثی جفت‌شونده با سدیم

SLC38A3
معین‌کننده‌ها
نام‌های دیگر	SLC38A3, G17, NAT1, SN1, SNAT3, solute carrier family 38 member 3
شناسه‌های بیرونی	OMIM: 604437 MGI: 1923507 HomoloGene: 4983 GeneCards: SLC38A3
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)[1]
End	107,669,530 bp[1]
الگوی گسترش RNA
	More reference expression data
هستی‌شناسی ژن
عملکرد ملکولی	• L-glutamine transmembrane transporter activity; • L-histidine transmembrane transporter activity; • L-asparagine transmembrane transporter activity; • L-alanine transmembrane transporter activity; • antiporter activity; • symporter activity; • amino acid transmembrane transporter activity;
ترکیبات سلولی	• integral component of membrane; • membrane; • پوسته یاخته; • integral component of plasma membrane; • basolateral plasma membrane;
فرایند زیستی	• L-alanine transport; • sodium ion transport; • histidine transport; • female pregnancy; • positive regulation of transcription from RNA polymerase II promoter in response to acidic pH; • positive regulation of glutamine transport; • brain development; • asparagine transport; • amino acid transport; • cellular response to potassium ion starvation; • glutamine transport; • ion transport; • amino acid transmembrane transport; • transmembrane transport; • L-histidine transmembrane transport;
	Sources:آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
	10991
	76257
	ENSG00000188338
	ENSMUSG00000010064
	Q99624
	Q9DCP2
	NM_006841، XR_001739987 XM_006712954، NM_006841، XR_001739987
	NM_001199218، NM_023805، XR_871103، XM_017313682، XM_030244696، XM_030244697 NM_001199217، NM_001199218، NM_023805، XR_871103، XM_017313682، XM_030244696، XM_030244697
	XP_006713017 NP_006832، XP_006713017
	NP_001186147، NP_076294، XP_030100556، XP_030100557، XP_036011271 NP_001186146، NP_001186147، NP_076294، XP_030100556، XP_030100557، XP_036011271
	ویکی‌داده
مشاهده/ویرایش Human	View/Edit Mouse

انتقال‌دهنده ۳ اسید آمینه خنثی جفت‌شونده با سدیم (انگلیسی: Sodium-coupled neutral amino acid transporter 3‎) یک پروتئین است که در انسان توسط ژن «SLC38A3» کُدگذاری می‌شود.[4][5][6]

منابع

GRCm38: Ensembl release 89: ENSMUSG00000010064 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Chaudhry FA, Reimer RJ, Krizaj D, Barber D, Storm-Mathisen J, Copenhagen DR, Edwards RH (Feb 2000). "Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission". Cell. 99 (7): 769–80. doi:10.1016/S0092-8674(00)81674-8. PMID 10619430.
Fei YJ, Sugawara M, Nakanishi T, Huang W, Wang H, Prasad PD, Leibach FH, Ganapathy V (Sep 2000). "Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+-coupled glutamine transporter". J Biol Chem. 275 (31): 23707–17. doi:10.1074/jbc.M002282200. PMID 10823827.
"Entrez Gene: SLC38A3 solute carrier family 38, member 3".

مشارکت‌کنندگان ویکی‌پدیا. «Sodium-coupled neutral amino acid transporter 3». در دانشنامهٔ ویکی‌پدیای انگلیسی، بازبینی‌شده در ۱۱ آوریل ۲۰۲۰.

برای مطالعهٔ بیشتر

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Sidoryk M, Matyja E, Dybel A, et al. (2004). "Increased expression of a glutamine transporter SNAT3 is a marker of malignant gliomas". NeuroReport. 15 (4): 575–8. doi:10.1097/00001756-200403220-00001. PMID 15094455.
Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMC 515316. PMID 15342556.
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Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
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Kholodnyuk ID, Kozireva S, Kost-Alimova M, et al. (2006). "Down regulation of 3p genes, LTF, SLC38A3 and DRR1, upon growth of human chromosome 3-mouse fibrosarcoma hybrids in severe combined immunodeficiency mice". Int. J. Cancer. 119 (1): 99–107. doi:10.1002/ijc.21794. PMID 16432833.
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[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000010064 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10619430-4] Chaudhry FA, Reimer RJ, Krizaj D, Barber D, Storm-Mathisen J, Copenhagen DR, Edwards RH (Feb 2000). "Molecular analysis of system N suggests novel physiological roles in nitrogen metabolism and synaptic transmission". Cell. 99 (7): 769–80. doi:10.1016/S0092-8674(00)81674-8. PMID 10619430.

[pmid10823827-5] Fei YJ, Sugawara M, Nakanishi T, Huang W, Wang H, Prasad PD, Leibach FH, Ganapathy V (Sep 2000). "Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+-coupled glutamine transporter". J Biol Chem. 275 (31): 23707–17. doi:10.1074/jbc.M002282200. PMID 10823827.

[entrez-6] "Entrez Gene: SLC38A3 solute carrier family 38, member 3".